NIH Begins Enrolling Volunteers in Clinical Trial for mRNA-Based Universal Flu Vaccine
Meanwhile, another trial using a new pancreatic cancer treatment using mRNA-technology shows promise.
The National Institutes of Health (NIH) recently announced that patients are now enrolling in an early-stage clinical trial to test a universal flu vaccine based on messenger RNA technology.
Scientists hope the vaccine will protect against a wide variety of flu strains and provide long-term immunity so people do not have to receive a shot every year.
Messenger RNA, or mRNA, is the technology behind Moderna’s and Pfizer
’s widely used Covid vaccines. NIH played a crucial role in developing the mRNA platform used by Moderna.
“A universal flu vaccine could serve as an important line of defense against the spread of a future flu pandemic,” Dr. Hugh Auchincloss, acting director of National Institute of Allergy and Infectious Diseases, said in a statement Monday.
The universal flu vaccine trial will enroll up to 50 healthy people ages 18 through 49 to test whether the experimental shot is safe and produces an immune response, according to NIH.
The groups will assist researchers in determining the best dosage. Once the optimal dosage has been determined, an additional ten participants will be vaccinated with it.
…””One of the big problems for flu is flu changes. By the time we pick the strains that go in the vaccines, by the time flu vaccines get manufactured, sometimes the strain can change some, or even during the season, from September to January or February, the flu strain can change as well,” said [Dr. Emmanuel Walter of the Duke Human Vaccine Institute, who serves as principal investigator leading the clinical trials].
…During Phase 1 of the trial, enrollees will be monitored for a year, and will receive different dosage levels, with a portion of participants used as a control group with the current vaccine. Researchers will study the vaccine’s safety and immune response, including how it holds up if the virus changes. Based off those results, it could be expanded to include other age groups.
While the effectiveness of the covid vaccines is questionable, and the results of the mRNA flu vaccine are being evaluated, researchers have used mRNA technology to create a pancreatic cancer treatment that is showing some astonishing results.
The vaccine provoked an immune response in half of the patients treated, and those people showed no relapse of their cancer during the course of the study, a finding that outside experts described as extremely promising.
The study, published in Nature, was a landmark in the yearslong movement to make cancer vaccines tailored to the tumors of individual patients.
Researchers at Memorial Sloan Kettering Cancer Center in New York, led by Dr. Vinod Balachandran, extracted patients’ tumors and shipped samples of them to Germany. There, scientists at BioNTech, the company that made a highly successful Covid vaccine with Pfizer, analyzed the genetic makeup of certain proteins on the surface of the cancer cells.
Using that genetic data, BioNTech scientists then produced personalized vaccines designed to teach each patient’s immune system to attack the tumors. Like BioNTech’s Covid shots, the cancer vaccines relied on messenger RNA. In this case, the vaccines instructed patients’ cells to make some of the same proteins found on their excised tumors, potentially provoking an immune response that would come in handy against actual cancer cells.
Hopefully, the pancreatic cancer treatment is proved to be a success and the flu vaccine will actually be a real vaccine that prevents infection and transmission.
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to the full extent allowed by law.
mRNA is aother name for poison, but profitable poison. The lemmings will rush to the doctor for a jab. Take it at your peril.
Before you enroll, look at what the Government has paid out through official channels to people who were injured by that other mRNA vaccine.
It wasn’t pretty.
“Stimulating an immune response” is not the same as conferring immunity.
As for the “longer lasting” aspect, these clowns can’t even get their “Covid” shot to last more than a few months at best.
Not holding my breath, and not buying anything these charlatans promote.
This is insane. Why do this? I can see that a new (any) treatment for pancreatic cancer is something we should look into. Maybe mRNA offers some hope on that front. But the flu? Why stop there? How about the common cold? One of the essential problems with mRNA technology is that it wasn’t ready for prime time. That does not mean it is without great promise. The technology has been around for a long time. And it has not delivered–yet. As to the flu. The flu shots don’t and never have worked. The flu isn’t cancer. The Republic will survive the flu.
No, the problem is that the medical establishment CHANGED THE DEFINITION of a vaccine to include their mRNA crap, and lying for years about it when it was clear it wasn’t working.
They’ve utterly destroyed their credibility on this front.
I would say that after covid and the way they handled that, mRNA technology is a dead-end. They couldn’t pay me enough to ever try it, especially after so many people injured by it and left to deal with the consequences for themselves after having supposedly done the “right” thing.
“I would say that after covid and the way they handled that, mRNA technology is a dead-end.”
To the contrary, it is the cause celebre of the leftist government, and it will now be inserted into everything from floor wax to dessert toppings.
You would think, by the same token, that after 20 years of escalating school shootings, the “gun free school zone” concept would be a dead end as well, wouldn’t you? Well, that’s not the way government works. When the patient pales, add more leeches.
I have yet to read how the infirmities of the mRNA gene therapy shots have been remedied. How have the problems of mRNA migration throughout the body and unregulated overproduction of the target protein been addressed? If somebody has that, I’d be pleased to get a link. There should have been multiple publications on these points, especially by the triumphant companies to their shareholders.
I would also be very interested to know how the new shots have obtained the reportedly wonderful results, and “will protect against a wide variety of flu strains and provide long-term immunity so people do not have to receive a shot every year.” These are entirely new results for flu.
Is this a broad-spectrum delivery vehicle for something like a whole-virus immunity? If so, again, how have the problems of mRNA migration throughout the body and unregulated overproduction of the target protein been addressed?
“I have yet to read how the infirmities of the mRNA gene therapy shots have been remedied.”
Silly goose. That’s why we need more volunteers!
Eggs, omelette, some breaking required.
I know. I keep expecting proof of scientific activity from “vaccine” companies.
Tell me you want to reduce the number of folks getting a flu shot without saying you want to reduce the number of folks getting a flu shot.
Now we know what the Great Filter is in the Fermi Paradox. Goodbye Earth.
Right. Because the medical establishment has such a STELLAR track record with mRNA so-called ‘vaccines’.
The ‘rona so-called ‘vaccine’ was a CATASTROPHIC failure. They lied for YEARS about it until they were finally forced to admit in the face of overwhelming evidence that it did NOTHING to prevent transmission.
And the very idea that a single ‘vaccine’ is somehow going to magically work against the fastest mutating disease in existence, who already has HUNDREDS of variants, is insane.
They can keep their mRNA crap.
It wouldn’t have been as bad, if the mRNA vaccines hadn’t had serious, sometimes fatal, side effects. And there is no evidence yet that the vaccine companies are addressing the basic weaknesses. The mRNA vaccines are hidden from the immune system by the substitution of N1 Methylpseudouridine for the Uridine found in normal RNA, and, as someone mentioned above, the production of spike proteins is unregulated, with the mRNA producing them until it is destroyed, along with the cells containing it (and exhibiting the antigenic spike proteins).
The reality is that after the first jab, the immune system has learned that the spike proteins are antigens, and automatically produces antibodies to fight them. That means that as long as there is spike producing mRNA in a human body (and that typically means upwards of 2 months), their immune system fights the spike proteins by producing antibodies keyed to the (mostly Wuhan variant) spike proteins. Getting an immune response to the proteins generated by the mRNA is the easy part. Turning it off is the step that they skipped. And until that is addressed, the mRNA flu vaccines are likely to be just as dangerous, even deadly, as their COVID-19 counterparts.
Can you address the reports that have shown the spike proteins in the vaccines are actually causing harm?
The mRNA vaccines for COVID-19 don’t have actual spikes in them. They contain artificial mRNA that produce Wuhan (first discovered) variant, and later Omicron variant (in the bivalent vaccines), spike proteins, when they get into cells. Then, after the first jab, when the immune system learns that the spike proteins produced by the artificial mRNA are antigens, it kills the cells it detects with the spike proteins. Many of the known side effects from the vaccines are a result of just that – the immune system killing cells presenting esp Wuhan variant spike proteins. Kill enough, say, heart muscle cells (presenting spike proteins), and the result is myocarditis. Etc.
As for cancer cells containing spike proteins – no surprise. At a high level, there are two types of cancer – slow growing and fast growing. Slow growing cancers involve cells that ignore signals to die. Fast growing cancers involve cells that divide (a lot) when they shouldn’t. It should surprise no one, if dividing cells containing artificial spike producing mRNA ended up with spike proteins in both resulting cells. And the mRNA if there is more than one strand of it.
But is there more? I don’t think that researchers know yet. Can a cancerous cell dividing duplicate the mRNA? I doubt it…but we really don’t know. It shouldn’t be able to happen. It would require either a full double transcription, or a transcription into DNA, which probably means inclusion into one of the 46 chromosomes in the subject’s cell. Once incorporated into the genome, they would naturally be duplicated at each cell division. There have been suggestions that that has been detected. Maybe.
Gotta evaluate the risk/reward. Pancreatic cancer is a killer, so a successful treatment, even with other risks would be a winner.
Flu? Not so much, at least for most people. So risks associated with the vaccine must be very low to make it worthwhile.
This sounds like another IQ test, as Covid was. I wonder, after Covid, how many will fail this one. They couldn’t pay me enough to inject that poison.
I’m an old codger, having seen over 80 summers. I have regularly taken the “real” flu vaccine every year for probably three decades. But I (wisely) rejected the Wu-flu pseudo “vaccine”. That so called “vaccine” was just a ploy for the Pharma-government industrial complex to poison folks worldwide.
“Begins Enrolling Volunteers in Clinical Trial”
I wouldn’t want to be in charge of that.
If I were, I’d start with a list of people still buying Bud Lite.
The few, the proud, the socially oblivious.
Just say NO! to any mRNA shot or therapy.
• • Meanwhile, another trial using a new pancreatic cancer treatment using mRNA-technology shows promise.
Really? To date no mRNA based technology has shown any promise. From the world-wide, experimental covid mRNA serum trials we are discovering that mRNA tech should never be used on human beings. Never.