Experts Assert ‘Rare’ Genome Sequencing Shows Coronavirus Bioengineered, Optimized for Human Infectivity
Also, Chinese medical researchers created mice with ‘humanized lungs’ mere months before the pandemic began, suggesting a gain-of-function focus.
Early last month, I reported on a classified study of SARS-CoV-2’s origin conducted a year ago by Lawrence Livermore National Laboratory scientists, the Department of Energy’s premier biodefense research institution. They determined the virus could have originated in a laboratory in China.
The study has attracted serious interest in Congress due to the administration’s order that U.S. intelligence agencies report within 90 days on how the virus emerged. The research focuses on the genome, which is the complete set of genetic information on the organism and can be used to trace the virus’s genetic history….natural or otherwise.
Lawrence Livermore has considerable expertise on biological issues. Its assessment drew on genomic analysis of the SARS-COV-2 virus, which causes Covid-19, they said.
Scientists analyze the genetic makeup of viruses to try to determine how they evolved and spread in the population. Proponents on both sides of the debate over the origins of Covid-19 have cited such analysis to try to make their case.
A spokeswoman for Lawrence Livermore declined to comment on the report, which remains secret.
The assessment is said to have been among the first U.S. government efforts to seriously explore the hypothesis that the virus leaked from China’s Wuhan Institute of Virology along with the competing hypothesis the pandemic began with human contact with infected animals.
Now, Drs Stephen Quay, CEO of biopharmaceutical company Atossa Therapeutics Inc, and Richard Muller, a physics professor at the University of California Berkeley, assert that “rare” genome sequences prove a Chinese lab bioengineered SARS-cov-2. The Wall Street Journal published the analysis on Sunday (emphasis is mine).
A genome is a blueprint for the factory of a cell to make proteins. The language is made up of three-letter “words” [i.e. codons] 64 in total, that represent the 20 different amino acids. For example, there are six different words for the amino acid arginine, the one that is often used in supercharging viruses. Every cell has a different preference for which word it likes to use most.
In the case of the gain-of-function supercharge, other sequences could have been spliced into this same site. Instead of a CGG-CGG (known as “double CGG”) that tells the protein factory to make two arginine amino acids in a row, you’ll obtain equal lethality by splicing any one of 35 of the other two-word combinations for double arginine. If the insertion takes place naturally, say through recombination, then one of those 35 other sequences is far more likely to appear; CGG is rarely used in the class of coronaviruses that can recombine with CoV-2.
In fact, in the entire class of coronaviruses that includes CoV-2, the CGG-CGG combination has never been found naturally. That means the common method of viruses picking up new skills, called recombination, cannot operate here. A virus simply cannot pick up a sequence from another virus if that sequence isn’t present in any other virus.
Quay and Muller point to the “double CGG” sequence as the “damning fact” suggesting a laboratory origin. Natural-origin believers would have to explain it away:
Proponents of zoonotic origin must explain why the novel coronavirus, when it mutated or recombined, happened to pick its least favorite combination, the double CGG,” they wrote. “Why did it replicate the choice the lab’s gain-of-function researchers would have made?
“At the minimum, this fact — that the coronavirus, with all its random possibilities, took the rare and unnatural combination used by human researchers — implies that the leading theory for the origin of the coronavirus must be laboratory escape.”
Quay and Muller also note that Chinese researchers use mice genetically modified to have the same coronavirus receptor in their lungs as humans, called “humanized mice.” Scientists repeatedly expose the mice to the virus to encourage adaptation. This approach is a hallmark of gain-of-function research. As a result, the coronavirus appears optimized for human infectivity.
Interestingly, the Chinese military medical researchers engineered these animals just months before the outbreak began.
The mice, developed using CRISPR gene-editing technology, were mentioned in an April 2020 study which researched their susceptibility to SARS-CoV-2, the virus that causes the COVID-19 illness, Vanity Fair revealed in its bombshell investigation.
Of the study’s 23 co-authors, 11 of them worked for the Academy of Military Medical Sciences, the medical research institute for the Chinese army.
Investigators with the U.S. National Security Council, researching the origins of the pandemic, determined that the mice referenced in the study were created in the summer of 2019 – just months before the emergence of the pandemic.
As I noted before, each addition to the coronavirus origin timeline is more disturbing than before.
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Was Fauci the only one in contact with the CCP medical researchers? What other Congressional members were in this loop with or through Fauci? When will the treason charges begin? The CCP may have wanted this outcome but they had to have had help from within our government!
Trump pointed the finger at Chia and the Dem knee-jerk reaction was to oppose. Boy do the Dems look stupid now. Everytime they try to hurt Trump – it seems to blow up in their face. Trump has some personality issues (but so does Pelosi et al). But at least he has sound policies and speaks the truth. Unlike the typical politicians. Dems seems to prefer form (virtue signaling) over substance (reality).
Next person who calls me a conspiracy theorist gets punched in the nose.
Better do it only over the Internet.
Except that almost no one will hear of it because the progressive fascist press won’t report it.🤬
Welp, that explains how they were able to come up with a gene-based “vaccine” so quickly. If you have the crib sheet, you can complete the exam in record time.
While I enjoyed the tongue in cheek spirit of your comment (and upvoted) I think I must be fair and clarify its inherent fallacy…
You can sequence any virus that you pick up with a swab in like a day. It’s no longer a huge limiting factor in vaccine development.
The big factors are figuring out what parts to target (the big target came to us as a “cheat sheet” from the spike protein in SARS-Cov1 that caused the Asian SARS outbreak circa 2004). Since it was biosimilar to Cov1, a lot of that part was easy.
At that point, you are left with using the recipe to design a safe and quality-controlled vaccine and running test protocols in cells, then animals, then human trials to determine safety and efficacy.
Trump sped that up by removing some FDA red tape and cooling periods and they can never take that away no matter how hard they try. In fact, they tried pretty hard before the election (by calling it “unsafe/unproven/untested”) then are shocked when post-election about half of the country is hesitant to get vaccinated. It’s really mind-numbing how some of our country on both sides of the political spectrum fail to recognize psychological manipulation from those in power and their media allies. It’s also angering to the point of immense frustration to let them get away with it and go around thinking that all of us are dumb simpleton peons that they can control (because they are able to control just enough useful idiots to be able to lie/steal/cheat their way to the finish line of gaining and holding power).
The cynics and skeptics read this right from day one. We’ve had Swine Flu, Bird Flu, SARS and all kinds of other previous pretenses to inoculate in order to subjugate.
“The Hand That Administers the Vaccine Is the Hand That Rules the World”
The Gripping Hand shoved a mote into our eyes…with apologies to Larry Niven and Jerry Pournelle.
Wow, China actually created something on their own, without stealing it?
With our money.
Possibly. It doesn’t work after all so the CCP ‘scientists’ may be responsible.
The Chinese created the virus in their Wuhan lab.
We’ve known this for at least a year. Not news, unless you’re informed exclusively by the MSM and Big Tech.
Several facts about the Wuflu are now beyond dispute:
1. Depending on which set of statistics you believe, the Wuflu was either slightly more deadly than the regular flu or slightly less deadly. As a super bio weapon it was a dud.
2. The victims of the Wuflu were overwhelmingly the elderly and those with pre-existing conditions – exactly the same populations the regular flu attacks.
3. The genetic makeup of the Wuflu point strongly towards being a deliberate laboratory creation rather than a natural mutation that somehow jumped from bats to humans.
4. The CDC and other federal agencies helped the Chinese develop deadly bio weapons. Tens of thousands of American politicians and bureaucrats are completely dirty.
5. Masks did little to no good.
6. The Joseph Goebbels media is evil (some things never change).
I would not call it a ‘dud’.
It caused major disruptions to the world economy and changed a lot in the political landscape. It gave all those dictator wannabes (not only in the U.S.) an opening to abuse power, limit freedoms, steal elections …
Yeah it’s not a dud at all. If you kill off everyone including your own citizens there’s no one left to rule.
I don’t think it’s a bioweapon, but if it were, it was almost perfect (except it was way too obviously traceable which means it was more than likely an accidental leak of a bioweapon in development).
Depends on how you look at it. The virus did not actually do the damage — it was used as an excuse for government to do the damage.
“As a super bio weapon it was a dud.”
Economic destruction, social and political upheaval, and destruction of a people’s freedoms and liberty – I’d say it was pretty effective, perhaps more as a psychological than a pathological weapon, but still, pretty effective.
Yes, the American people allowed themselves to be herded into a state of panic, allowed the government to take away our freedoms and designate which of us were “essential” and ‘Non-essential,” blindly followed stupid advice from stupid, self-serving, politicized, and conflicted ‘elites” and “experts”, trusting them more than our fellow common citizens and our own common sense.
Boys and girls, and everyone else somewhere in between or beyond that spectrum, the Chinese made it, we helped pay for it, and when the inevitable accident occurred, we collectively lost our cool and fled from all reason. Don’t deny it. Do you recall the panic buying when all this started? The abject fear of the people?
Perhaps you stood firm in calm and reason. But if so, your were a mere pebble in the stream.
Lots of blame to go around here folks. There are a lot of things that need to be gotten rid of and changed, like Anthony Fauci, but just do not let people scapegoat away from themselves. There is a long, long list.
Let’s start by outlawing gain of function experimentation permanently, clearly, and forever. Let’s cleanse the government of people who thought gain in function experiments were a good idea. Let’s hold the global corporatist fascists to account who actively blocked truth and promoted lies in concert with self-interested government officials who conspired against our physical, psychological, financial, social, and political health.
Remember who they all are. Remember what they did. Hold them all to account.
You also have the folks at big pharma deep into this as well. Many pointed out the cheap effective treatments of things like vitamin D, and HCQ were blocked as prevention and treatment options. Instead they pushed the costly drugs that lined their pockets with government cash. Add in the testing protocols where the samples were cycled so many more times than usual to get more positive results add to the mix the number of false positives as well.
I think word has really gotten out, even in the deep blue State of California. When I talk to people, I mention the upside: now we have a cure for the common cold. They agree,
I’m seeing zinc and zinc plus either “elderberry” or “green tea” extracts everywhere. Those last two items are known food sources for zinc ionophores. Zinc is also showing up in slightly higher doses in daily multivitamins, as is D.
So yeah, I think word is out.
Creators of a bio-weapon could not have known that the world’s political “leadership” would go completely mental over the flu. That’s not a good plan for an effective bio-weapon. In hindsight, that’s what happened, but no planner would have released a weapon that depended upon what, before the event, would have been considered an unlikely response.
That’s why you had to couple the virus release withe the news coverage of people being welded into their apartments and the release on social media of those mysterious “zombie” videos of people just falling dead on the sidewalk as they went about their daily business. All of the news stories were all designed to prep us to accept the stampede by governments to shut things down.
this dud rid the chinese government of non productive servants and completely upended world economy and any tarriffs against china.
yup. real f*ing dud….
Recovering Lutheran: 1. Depending on which set of statistics you believe, the Wuflu was either slightly more deadly than the regular flu or slightly less deadly.
In the U.S., there have been about 600,000 deaths attributable to COVID-19, a number supported by estimates of excess deaths over the same period. That is at least ten times the number of deaths during a bad flu season. Many other countries have also seen high numbers of death. The pandemic only abated because of the introduction of effective vaccines, or the final death toll would almost certainly be higher.
It was always a bio-weapon, but there was a deliberate attempt to hide this fact.
The one question now is: Why the shift?
There must be something, some reason why it’s now convenient to start talking about the forbidden topic.
“The one question now is: Why the shift?”
Because Trump is gone, but that is only a partial reason. Why now admit he was right? It’s a solid question. I would be interested in people’s opinion.
IMO, the simple fact is that the official line hasn’t made much sense from the start. The lab leak theory is the simplest explanation and based on the Chinese efforts to deliberately obscure and then actively resist any meaningful inquiry that theory holds up.
Further the basic knowledge about how a virus works and spreads or how to determine it’s level of lethality isn’t restricted to ‘experts’. When the laity asked basic questions about the public health response and were ignored at best and vilified at worst then every skeptical person was correctly made more resistant to the regime of lockdown.
Finally, there were dissenting voices from within the scientific community pointing out the misguided nature of the lockdown, off the shelf measures to boost immune systems and resistance, treatment alternatives to ventilation ECT. Despite the attempts to vilify and silence these voices their message got out to the public.
So in combination, the legacy media and social media platforms which worked hand in hand with public health officials to promote their narrative and quash dissent have finally realized that too many people understand exactly what they were up to. They are now backpedaling. IMO, they will throw Fauchi under the bus within two months in the hope that sacrifice will appease a restless and PO public.
They were also trying to cover up the fact that the US government was funding this research, from both agencies managed by Fauci and Collins and the state department. I’m waiting for the expose as to the State Department’s role in this,. From what I have read the State Department is in this deeper than the NIH.
Well yeah… The grants are the excuse to can Fauchi. The public health community does not want the coming scrutiny. Their pronouncements were not based on objective facts. Their use of consistently flawed models to drive policy even when the predictive value was off by orders of magnitude from observed data has become mainstream knowledge.
The emperor has no clothes and in the case of Rona the experts have shown no expertise.
Why the shift? Oh, that’s easy. The Western countries have belatedly come to the realization that China and the CCP are actually not our friends and that China’s worldwide political and military shenanigans aren’t happening for our benefit. So there is no real reason to keep up with the pretense that the SARS-CoV-2 virus wasn’t manufactured and released as a bio-weapon against the Western countries. The Western countries are now building a case against China to prepare citizens for the eventual conclusion of the war that China started with this bio-weapon and pandemic. And it ain’t gonna be pretty. That’s for certain.
They conveniently came to that realization after seizing power. I don’t think that was an accident.
China wanted Trump out, and the Democrats assisted with the pallet of cash given to “Iran” a few years ago….probably from SS
Harris looks like a football player with breasts. It is hard to understand why anyone would marry her.
We already know for sure that it was not. Naturally occurring regional outbreaks are documented going back into 2019.
Please cite your sources for naturally occurring occurrences of this virus in 2019..
There were occurrences, possibly in September, definitely in December with the Chicoms attributing the infections to animal to human transfer, looking less likely with each day.. I am waiting for your response.
There’s an oft quoted saying about human nature and problem solving. It goes something like “There is always a solution; quick, plausible, and wrong”. Applies here to libs, eh?
“Scientists repeatedly expose the mice to the virus to encourage adaptation. This approach is a hallmark of gain-of-function research. As a result, the coronavirus appears optimized for human infectivity.”
This is why there can’t be a natural “intermediate” vector between the original bat virus and human corona virus – the corona virus is maximally adapted to humans (because it was likely maximally adapted to a genetically engineered animal used as a human substitute). In nature, such a virus would be maladapted to its animal host, and would have been deselected for its inability to effectively and efficiently bind to its host’s cells, and therefore would have failed to replicate. It would have been an evolutionary dead-end, winning the Darwin Award for “worst mutation in a corona virus.”
Viruses that do jump from animals to humans do so when they are able – that is, when they have adequate adaptations to bind to, and replicate in, human cells, and when they have an opportunity to do so. Only then do successive waves of replication (in hundreds of thousands, or even millions of people) give rise to mutations that, by chance, improve a virus’s efficiency and effectiveness at transmission and replication within the new host. (Viruses tend to evolve in two directions at the same time – towards greater transmissibility and less lethality – because together these mutations increase a virus’s ability to do what it is meant to do – replicate. A virus can’t replicate as much if it doesn’t transmit easily from one host to another, or if it kills too many of its hosts before it has an opportunity for transmission.) These earlier version of SARS2, that were sub-optimally evolved for a human host, were not seen anywhere, but would have been seen in a naturally-evolved virus.
We need to know the names of the 27 “Scientists” who said the leak of the virus from the Chinese lab was impossible.
I think their credibility is questionable and any future statement from them should be ignored>